Mnttm1.1Phu
Targeted Allele Detail
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| Symbol: |
Mnttm1.1Phu |
| Name: |
max binding protein; targeted mutation 1.1, Peter J Hurlin |
| MGI ID: |
MGI:2678322 |
| Synonyms: |
Mnt- |
| Gene: |
Mnt Location: Chr11:74721746-74736551 bp, + strand Genetic Position: Chr11, 45.76 cM, cytoband B-C
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| Alliance: |
Mnttm1.1Phu page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:85481
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: Mice heterozygous for Mnttm1Phu were crossed with transgenic mice carryingTgN(EIIa-cre)C5379Lmgd. In mice carrying both the transgene and Mnttm1Phu, cre excision removed exons 4 to 6 as well as the Hygro selection cassette. The predicted protein product would thus lack the C-terminal amino acids from residue 235 to 591. No mRNA transcripts were identified by RT-PCR in embryos homozygous for this disruption.
(J:85481)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Mnt Mutation: |
26 strains or lines available
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| Original: |
J:85481 Hurlin PJ, et al., Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. EMBO J. 2003 Sep 15;22(18):4584-96 |
| All: |
2 reference(s) |
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Analysis Tools
