Tg(Nppa-cre)3Vmc
Transgene Detail
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| Symbol: |
Tg(Nppa-cre)3Vmc |
| Name: |
transgene insertion 3, Vincent M Christoffels |
| MGI ID: |
MGI:2679329 |
| Synonyms: |
-3/+4mCre, Nppa-Cre3 |
| Transgene: |
Tg(Nppa-cre)3Vmc Location: unknown
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| Alliance: |
Tg(Nppa-cre)3Vmc page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Nppa-cre)3Vmc expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Nppa (MGI:97367) |
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Mutation details: The transgenic construct consisted of a sequence fragment encoding cre recombinase, a nuclear localization signal, and a consensus Kozak signal inserted at the start codon of the mouse genomic Nppa sequence. The 0.7 kbp Nppa proximal promoter region (-3kbp to +4 kbp relative to the transcription start site) was included. The mouse Nppa proximal promoter drives expression of cre recombinase in atrial cardiomyocytes beginning around E10.5. Complete expression is observed around E14.5. Some expression was observed in the inflow tract. Greater atrial specificity resulted in further analysis of this mouse line.
(J:86158)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Nppa
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:86158 de Lange FJ, et al., Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment. Genesis. 2003 Sep;37(1):1-4 |
| All: |
6 reference(s) |
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Analysis Tools
