Tg(Tcra/Tcrb)1Vbo Transgene Detail MGI Mouse (MGI:2680176)

Tg(Tcra/Tcrb)1Vbo
Transgene Detail

Summary

Symbol:	Tg(Tcra/Tcrb)1Vbo
Name:	transgene insertion 1, Harald von Boehmer
MGI ID:	MGI:2680176
Synonyms:	6.5 TcR, HA TCR, SFE TCR, TCR-HA, TCR-SFE, TS1
Transgene:	Tg(Tcra/Tcrb)1Vbo Location: unknown
Alliance:	Tg(Tcra/Tcrb)1Vbo page

Transgene
origin

Strain of Origin:

(C57BL/6J x DBA/2J)F2

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence)

Mutation:

Insertion

Tg(Tcra/Tcrb)1Vbo expresses 2 genes

Mutation details: The transgenic construct expresses a T cell receptor specific for peptide 111-119 from influenza hemagglutinin (HA), presented by class II I-E^d MHC molecules. The receptor is encoded by Tcrb-V8.2, Tcrb-J, Tcra-V4, and Tcra-J. (J:86429)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:86429 Kirberg J, et al., Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor. J Exp Med. 1994 Jul 1;180(1):25-34
All:	98 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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