Sncgtm1Vlb
Targeted Allele Detail
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| Symbol: |
Sncgtm1Vlb |
| Name: |
synuclein, gamma; targeted mutation 1, Vladimir L Buchman |
| MGI ID: |
MGI:2683142 |
| Synonyms: |
TgHSNCGtm1VLB |
| Gene: |
Sncg Location: Chr14:34092231-34096626 bp, - strand Genetic Position: Chr14, 20.81 cM, cytoband B-C
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| Alliance: |
Sncgtm1Vlb page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:86439
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| Parent Cell Line: |
E14TG2a (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 through 3 were replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected in homozygous mutant mice by Northern blot analysis of RNA obtained from various tissues. Western blot analysis of total spinal cord protein indicated an absence of protein in homozygous mutant mice.
(J:86439)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Original: |
J:86439 Ninkina N, et al., Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene. Mol Cell Biol. 2003 Nov;23(22):8233-45 |
| All: |
19 reference(s) |
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Analysis Tools
