Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(PTH-cre)4167Slib
Name:	transgene insertion 4167, Steven K Libutti
MGI ID:	MGI:2683304
Synonyms:	PTH-cre, Tg(PTH-cre)1Slib
Transgene:	Tg(PTH-cre)4167Slib  Location: unknown
Alliance:	Tg(PTH-cre)4167Slib page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(PTH-cre)4167Slib expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human PTH (5741) Pth  (MGI:97799)   Mutation details: A 5' upstream regulatory region of the human PTH gene was adjoined to sequence encoding cre recombinase followed by a metallothionein 1 polyadenylation signal. The expression of cre recombinase is parathyroid cell specific. (J:86642)

Activity:	Tissue activity of this recombinase allele
Driver:	PTH (human) Summary of all recombinase alleles driven by PTH. Comparative matrix view of recombinase activities Alliance human PTH gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(PTH-cre)4167Slib

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:86642 Libutti SK, et al., Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. Cancer Res. 2003 Nov 15;63(22):8022-8
All:	13 reference(s)