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Mrgpra3 Gene Detail
Summary
  • Symbol
    Mrgpra3
  • Name
    MAS-related GPR, member A3
  • Synonyms
    G protein-coupled receptor, MrgA3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684085
    NCBI Gene: 233222
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:47238698-47251120 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 30.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    692 from dbSNP Build 142
  • Strain Annotations
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684085
 protein coding gene Chr7:47238698-47251120 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0032768
 protein coding gene Chr7:50344209-50357588 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0032785
 protein coding gene Chr7:47675578-47895945 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MRGPRX1, MAS related GPR family member X1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRGPRX1, MAS related GPR family member X1
  • Synonyms
    GPCR, MGRG2, MRGX1, SNSR4
  • Links
    NCBI Gene ID: 259249
    neXtProt AC: NX_Q96LB2
    UniProt: Q96LB2

  • Chr Location
    11p15.1,11; chr11:18933499-18939414 (-)  GRCh38
  • Human Ortholog
    MRGPRX2, MAS related GPR family member X2
  • Synonyms
    MGRG3, MRGX2
  • Links
    NCBI Gene ID: 117194
    neXtProt AC: NX_Q96LB1
    UniProt: Q96LB1

  • Chr Location
    11p15.1; chr11:19054455-19060717 (-)  GRCh38
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
  • Synonyms
    GPCR, MRGX3, SNSR1, SNSR2
  • Links
    NCBI Gene ID: 117195
    neXtProt AC: NX_Q96LB0
    UniProt: Q96LB0

  • Chr Location
    11p15.1; chr11:18120955-18138488 (+)  GRCh38
  • Human Ortholog
    MRGPRX4, MAS related GPR family member X4
  • Synonyms
    GPCR, MRGX4, SNSR6
  • Links
    NCBI Gene ID: 117196
    neXtProt AC: NX_Q96LA9
    UniProt: Q96LA9

  • Chr Location
    11p15.1; chr11:18172837-18174280 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    4
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 233222 NCBI Gene Model | MGI Sequence Detail 12423 C57BL/6J ±  kb
transcript NM_153067 RefSeq | MGI Sequence Detail 1295 C57BL/6  
polypeptide Q91WW3 UniProt | EBI | MGI Sequence Detail 302 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    Other 3

    Microarray probesets 2
References
more
  • Summaries
    All 41
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
  • Latest
    J:343323 Deng L, et al., S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Cell. 2023 Nov 22;186(24):5375-5393.e25
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory