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Tg(Pdx1-cre/Esr1*)35.6Dam
Transgene Detail
Summary
Symbol: Tg(Pdx1-cre/Esr1*)35.6Dam
Name: transgene insertion 35.6, Douglas A Melton
MGI ID: MGI:2684319
Synonyms: Tg(Ipf1-cre/Esr1)35.6Dam, Tg(Pdx1-cre/Esr1)35.6Dam
Transgene: Tg(Pdx1-cre/Esr1*)35.6Dam  Location: unknown  
Alliance: Tg(Pdx1-cre/Esr1*)35.6Dam page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Pdx1-cre/Esr1*)35.6Dam expression driven by 1 gene
 
Mutation details: The sequence encoding a tamoxifen-inducible form of a cre recombinase/estrogen receptor fusion protein was adjoined to the Ipf1 promoter to drive mosaic expression of cre recombinase in endocrine, exocrine, and duct tissue of the pancreas. (J:76095)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdx1 (species not specified)
Summary of all recombinase alleles driven by Pdx1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:76095 Gu G, et al., Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development. 2002 May;129(10):2447-57
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory