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Tg(Pdx1-cre/Esr1*)35.10Dam
Transgene Detail
Summary
Symbol: Tg(Pdx1-cre/Esr1*)35.10Dam
Name: transgene insertion 35.10, Douglas A Melton
MGI ID: MGI:2684321
Synonyms: Pdx1CreERT, Pdx1-Cre-ERTM, Pdx-creERt2, Tg(Ipf1-cre/Esr1)35.10Dam, Tg(Pdx1-cre/Esr1)35.10Dam
Transgene: Tg(Pdx1-cre/Esr1*)35.10Dam  Location: unknown  
Alliance: Tg(Pdx1-cre/Esr1*)35.10Dam page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Pdx1-cre/Esr1*)35.10Dam expression driven by 1 gene
 
Mutation details: Sequence encoding a tamoxifen inducible form of a cre recombinase/estrogen receptor fusion protein was adjoined to the Pdx1 promoter to drive mosaic expression of cre recombinase in endocrine, exocrine, and duct tissue of the pancreas. (J:76095)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pdx1 (species not specified)
Summary of all recombinase alleles driven by Pdx1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:76095 Gu G, et al., Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development. 2002 May;129(10):2447-57
All:  45 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory