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Sdr16c6 Gene Detail
Summary
  • Symbol
    Sdr16c6
  • Name
    short chain dehydrogenase/reductase family 16C, member 6
  • Synonyms
    4833413O15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685269
    NCBI Gene: 242286
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:4055926-4077514 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 2.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    516 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685269
 protein coding gene Chr4:4055926-4077522 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028029
 protein coding gene Chr4:542062-565768 (-)
A/J MGP_AJ_G0027987
 protein coding gene Chr4:620973-646918 (-)
AKR/J MGP_AKRJ_G0027953
 protein coding gene Chr4:558697-581526 (-)
BALB/cJ MGP_BALBcJ_G0027999
 protein coding gene Chr4:573342-601139 (-)
C3H/HeJ MGP_C3HHeJ_G0027729
 protein coding gene Chr4:728598-752719 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028442
 protein coding gene Chr4:726175-748970 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025786
 protein coding gene Chr4:558118-577523 (-)
CAST/EiJ MGP_CASTEiJ_G0027182
 protein coding gene Chr4:632179-654947 (-)
CBA/J MGP_CBAJ_G0027704
 protein coding gene Chr4:595393-618727 (-)
DBA/2J MGP_DBA2J_G0027844
 protein coding gene Chr4:580347-617568 (-)
FVB/NJ MGP_FVBNJ_G0027811
 protein coding gene Chr4:513653-536889 (-)
LP/J MGP_LPJ_G0027955
 protein coding gene Chr4:591861-621067 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027844
 protein coding gene Chr4:771539-801132 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028501
 protein coding gene Chr4:552000-576020 (-)
PWK/PhJ MGP_PWKPhJ_G0026904
 protein coding gene Chr4:663273-685339 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026734
 protein coding gene Chr4:584637-612870 (-)
WSB/EiJ MGP_WSBEiJ_G0027262
 protein coding gene Chr4:701762-724873 (-)



Homology
more
  • Human Ortholog
    SDR16C6P, short chain dehydrogenase/reductase family 16C member 6, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SDR16C6P, short chain dehydrogenase/reductase family 16C member 6, pseudogene
  • Synonyms
    SDR16C6
  • Links
    NCBI Gene ID: 442388

  • Chr Location
    8q12.1; chr8:56373064-56395365 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    4 phenotype references
Mice homozygous for a knock-out allele are viable and fertile. Mice homozygous for a deletion of Sdr16c5 and Sdr16c6 exhibit accelerated hair growth enlarged meibomian glands.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 242286 NCBI Gene Model | MGI Sequence Detail 21589 C57BL/6J ±  kb
transcript NM_001080710 RefSeq | MGI Sequence Detail 1181 Not Specified  
polypeptide Q05A13 UniProt | EBI | MGI Sequence Detail 316 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
  • Latest
    J:340060 Butovich IA, et al., Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis. J Biol Chem. 2023 Apr 17;299(6):104725
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory