About   Help   FAQ
Acte1 Gene Detail
Summary
  • Symbol
    Acte1
  • Name
    actin, epsilon 1
  • Synonyms
    Gm498, LOC244239
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685344
    NCBI Gene: 102636989
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:143420575-143453780 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 88.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    918 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685344
 protein coding gene Chr7:143420575-143453783 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033285
 protein coding gene Chr7:149197022-149229388 (+)
A/J MGP_AJ_G0033268
 protein coding gene Chr7:144862885-144893972 (+)
AKR/J MGP_AKRJ_G0033199
 protein coding gene Chr7:148950088-148984279 (+)
BALB/cJ MGP_BALBcJ_G0033268
 protein coding gene Chr7:144646644-144681322 (+)
C3H/HeJ MGP_C3HHeJ_G0032982
 protein coding gene Chr7:148705314-148746203 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033778
 protein coding gene Chr7:154598176-154633748 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030751
 protein coding gene Chr7:146015845-146048550 (+)
CAST/EiJ MGP_CASTEiJ_G0032305
 protein coding gene Chr7:141005799-141039705 (+)
CBA/J MGP_CBAJ_G0032955
 protein coding gene Chr7:159845178-159881995 (+)
DBA/2J MGP_DBA2J_G0033109
 protein coding gene Chr7:142845405-142876844 (+)
FVB/NJ MGP_FVBNJ_G0033057
 protein coding gene Chr7:142783127-142815805 (+)
LP/J MGP_LPJ_G0033201
 protein coding gene Chr7:150739761-150773841 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033091
 protein coding gene Chr7:160435195-160469916 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033796
 protein coding gene Chr7:147903018-147939420 (+)
PWK/PhJ MGP_PWKPhJ_G0032015
 protein coding gene Chr7:136138761-136170660 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031859
 protein coding gene Chr7:134684235-134723909 (+)
WSB/EiJ MGP_WSBEiJ_G0032418
 protein coding gene Chr7:148884603-148919858 (+)



Homology
more
  • Human Ortholog
    ACTE1P, actin epsilon 1, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTE1P, actin epsilon 1, pseudogene
  • Links
    NCBI Gene ID: 399923
    UniProt: Q6ZVU0

  • Chr Location
    11q13.4; chr11:71382456-71423730 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 102636989 NCBI Gene Model | MGI Sequence Detail 33206 C57BL/6J ±  kb
transcript NM_001369837 RefSeq | MGI Sequence Detail 1650 C57BL/6  
polypeptide NP_001356763 RefSeq | MGI Sequence Detail 382 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    9 Sequences
  • InterPro Domains
    IPR004000 Actin family
    IPR043129 ATPase, nucleotide binding domain
Other
Accession IDs
less
MGI:6273324
References
more
  • Summaries
    All 12
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory