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Gnai1tm1Drs
Targeted Allele Detail
Summary
Symbol: Gnai1tm1Drs
Name: G protein subunit alpha i1; targeted mutation 1, Daniel R Storm
MGI ID: MGI:3028010
Synonyms: Gia1 -
Gene: Gnai1  Location: Chr5:18470133-18565353 bp, - strand  Genetic Position: Chr5, 8.16 cM
Alliance: Gnai1tm1Drs page
Rib and sternum defects in mice with mutations of Gnai1, Gnai2, and/or Gnai3

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87423
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin cassette was spliced into exon3. Western blot analysis confirmed the absence of gene product. (J:87423)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gnai1 Mutation:  15 strains or lines available
References
Original:  J:87423 Pineda VV, et al., Removal of G(ialpha1) Constraints on Adenylyl Cyclase in the Hippocampus Enhances LTP and Impairs Memory Formation. Neuron. 2004 Jan 8;41(1):153-63
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory