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En1tm2(cre)Gld
Targeted Allele Detail
Summary
Symbol: En1tm2(cre)Gld
Name: engrailed 1; targeted mutation 2, Martyn Goulding
MGI ID: MGI:3029756
Synonyms: En1Cre, En1KICre
Gene: En1  Location: Chr1:120530246-120535719 bp, + strand  Genetic Position: Chr1, 52.74 cM, cytoband C2-qter
Alliance: En1tm2(cre)Gld page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87771
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
En1tm2(cre)Gld expression driven by 1 gene
 
Mutation details: A cassette containing cre followed by PGK-neo was inserted into exon 1 of the endogenous locus, replacing the start codon and sequence encoding the first 72 amino acids. Cre recombinase is expressed via the endogenous promoter. (J:87771)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: En1 (mouse)
Summary of all recombinase alleles driven by En1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any En1 Mutation:  34 strains or lines available
References
Original:  J:87771 Sapir T, et al., Pax6 and engrailed 1 regulate two distinct aspects of renshaw cell development. J Neurosci. 2004 Feb 4;24(5):1255-64
All:  18 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory