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Mrgprb8 Gene Detail
Summary
  • Symbol
    Mrgprb8
  • Name
    MAS-related GPR, member B8
  • Synonyms
    MrgB8
  • Feature Type
    protein coding gene
  • IDs
    MGI:3033134
    NCBI Gene: 404240
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:48038274-48039396 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 31.11 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    311 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3033134
 protein coding gene Chr7:48038274-48039396 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032289
 protein coding gene Chr7:49018177-49019299 (+)
A/J MGP_AJ_G0032268
 protein coding gene Chr7:48293167-48294289 (+)
AKR/J MGP_AKRJ_G0032204
 protein coding gene Chr7:49460237-49461359 (+)
BALB/cJ MGP_BALBcJ_G0032280
 protein coding gene Chr7:47956858-47957980 (+)
C3H/HeJ MGP_C3HHeJ_G0031993
 protein coding gene Chr7:49813753-49814875 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032773
 protein coding gene Chr7:51256094-51257216 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029780
 protein coding gene Chr7:51478924-51480055 (+)
CAST/EiJ MGP_CASTEiJ_G0031321
 protein coding gene Chr7:41242160-41243282 (+)
CBA/J MGP_CBAJ_G0031958
 protein coding gene Chr7:53014409-53015531 (+)
DBA/2J MGP_DBA2J_G0032115
 protein coding gene Chr7:47512429-47513551 (+)
FVB/NJ MGP_FVBNJ_G0032069
 protein coding gene Chr7:47467879-47469001 (+)
LP/J MGP_LPJ_G0032196
 protein coding gene Chr7:49953960-49955082 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032106
 protein coding gene Chr7:52141641-52143423 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032790
 protein coding gene Chr7:48436091-48437213 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030882
 protein coding gene Chr7:36585152-36586274 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MRGPRX1, MAS related GPR family member X1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRGPRX1, MAS related GPR family member X1
  • Synonyms
    GPCR, MGRG2, MRGX1, SNSR4
  • Links
    NCBI Gene ID: 259249
    neXtProt AC: NX_Q96LB2
    UniProt: Q96LB2

  • Chr Location
    11p15.1,11; chr11:18933499-18939414 (-)  GRCh38
  • Human Ortholog
    MRGPRX2, MAS related GPR family member X2
  • Synonyms
    MGRG3, MRGX2
  • Links
    NCBI Gene ID: 117194
    neXtProt AC: NX_Q96LB1
    UniProt: Q96LB1

  • Chr Location
    11p15.1; chr11:19054455-19060717 (-)  GRCh38
  • Human Ortholog
    MRGPRX3, MAS related GPR family member X3
  • Synonyms
    GPCR, MRGX3, SNSR1, SNSR2
  • Links
    NCBI Gene ID: 117195
    neXtProt AC: NX_Q96LB0
    UniProt: Q96LB0

  • Chr Location
    11p15.1; chr11:18120955-18138488 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 404240 NCBI Gene Model | MGI Sequence Detail 1123 C57BL/6J ±  kb
transcript NM_207539 RefSeq | MGI Sequence Detail 1123 Not Specified  
polypeptide Q7TN51 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory