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StrbpGt(pGT1.8geo)8Pgr
Gene trapped Allele Detail
Summary
Symbol: StrbpGt(pGT1.8geo)8Pgr
Name: spermatid perinuclear RNA binding protein; gene trap 8, Peter Gruss
MGI ID: MGI:3033751
Synonyms: SpnrGT
Gene: Strbp  Location: Chr2:37459880-37593890 bp, - strand  Genetic Position: Chr2, 24.19 cM, cytoband C1
Alliance: StrbpGt(pGT1.8geo)8Pgr page
Mutation
origin
Mutant Cell Line:  VII-28
Germline Transmission:  Earliest citation of germline transmission: J:69466
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Gene trapped (Hypomorph, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pSABetageo     Vector Type: gene trap
 
Mutation detailsA gene trap vector inserted into the endogenous gene such that the beta-galactosidase and neomycin genes were fused to the expressed mRNA at position 1149. Beta-galactosidase expression was noted in a similar pattern to the wild-type mRNA. RT-PCR analysis indicated that a low level of wild-type transcript was still expressed from this allele, suggesting that this mutation is a hypomorph. (J:69466)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Strbp Mutation:  46 strains or lines available
References
Original:  J:47980 Stoykova A, et al., Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system. Dev Dyn. 1998 Jun;212(2):198-213
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory