Endog/D2Wsu81etm1Mxu
Targeted Allele Detail
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| Symbol: |
Endog/D2Wsu81etm1Mxu |
| Name: |
endonuclease G; targeted mutation 1, Ming Xu |
| MGI ID: |
MGI:3034030 |
| Synonyms: |
EndoG-, Endogtm1Mxu |
| Gene: |
Endog Location: Chr2:30061525-30064057 bp, + strand Genetic Position: Chr2, 21.29 cM, cytoband B
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| Alliance: |
Endog/D2Wsu81etm1Mxu page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:88144
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intergenic deletion
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Mutation details: The majority of the 3 exons of the Endog and 5 of 10 exons of D2Wsu81e (which overlaps exon 3 of Endog) were replaced with a neomycin selection cassette inserted by homologous recombination. Reduced ENDOG protein levels were detected by Western blot analysis of protein extracts obtained from heterozygous MEFs and hearts.
(J:88144, J:94752)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Endog Mutation: |
12 strains or lines available
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| Original: |
J:88144 Zhang J, et al., Endonuclease G is required for early embryogenesis and normal apoptosis in mice. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15782-7 |
| All: |
2 reference(s) |
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Analysis Tools
