Ar<tm1.1Verh> Targeted Allele Detail MGI Mouse (MGI:3034099)

Ar^tm1.1Verh
Targeted Allele Detail

Summary

Symbol:	Ar^tm1.1Verh
Name:	androgen receptor; targeted mutation 1.1, Guido Verhoeven
MGI ID:	MGI:3034099
Synonyms:	ARKO
Gene:	Ar Location: ChrX:97192375-97366821 bp, + strand Genetic Position: ChrX, 42.82 cM
Alliance:	Ar^tm1.1Verh page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:88169
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Intragenic deletion
		Mutation details: Exon 2 was deleted in the germline via cre mediated recombination of the loxP sites in Ar^tm1Verh. (J:88169)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ar Mutation:	23 strains or lines available

References

Original:	J:88169 De Gendt K, et al., A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1327-32
All:	22 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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