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Arhgef39 Gene Detail
Summary
  • Symbol
    Arhgef39
  • Name
    Rho guanine nucleotide exchange factor 39
  • Synonyms
    E130306D19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3036286
    NCBI Gene: 230098
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:43496142-43499695 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 23.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3036286
 protein coding gene Chr4:43496139-43508747 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028209
 protein coding gene Chr4:41613848-41617401 (-)
A/J MGP_AJ_G0028165
 protein coding gene Chr4:40138037-40141590 (-)
AKR/J MGP_AKRJ_G0028117
 protein coding gene Chr4:41050379-41053932 (-)
BALB/cJ MGP_BALBcJ_G0028185
 protein coding gene Chr4:40225508-40229061 (-)
C3H/HeJ MGP_C3HHeJ_G0027907
 protein coding gene Chr4:41675713-41679266 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028626
 protein coding gene Chr4:43175293-43178846 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025938
 protein coding gene Chr4:37584956-37588736 (-)
CAST/EiJ MGP_CASTEiJ_G0027347
 protein coding gene Chr4:41179510-41183055 (-)
CBA/J MGP_CBAJ_G0027873
 protein coding gene Chr4:44478997-44482550 (-)
DBA/2J MGP_DBA2J_G0028022
 protein coding gene Chr4:40046530-40050083 (-)
FVB/NJ MGP_FVBNJ_G0027989
 protein coding gene Chr4:39267892-39271445 (-)
LP/J MGP_LPJ_G0028121
 protein coding gene Chr4:41665198-41668751 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028013
 protein coding gene Chr4:47749329-47752882 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028662
 protein coding gene Chr4:41243889-41247442 (-)
PWK/PhJ MGP_PWKPhJ_G0027073
 protein coding gene Chr4:40090797-40094343 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026901
 protein coding gene Chr4:40831240-40834803 (-)
WSB/EiJ MGP_WSBEiJ_G0027427
 protein coding gene Chr4:41145641-41149198 (-)



Homology
more
  • Human Ortholog
    ARHGEF39, Rho guanine nucleotide exchange factor 39
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARHGEF39, Rho guanine nucleotide exchange factor 39
  • Synonyms
    C9orf100
  • Links
    NCBI Gene ID: 84904
    neXtProt AC: NX_Q8N4T4
    UniProt: Q8N4T4

  • Chr Location
    9p13.3; chr9:35658875-35675866 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Arhgef39
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    18 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    29
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051517 Ensembl Gene Model | MGI Sequence Detail 3554 C57BL/6J ±  kb
transcript ENSMUST00000054538 Ensembl | MGI Sequence Detail 1659 Not Applicable  
polypeptide ENSMUSP00000055293 Ensembl | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory