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Tg(Kit-cre)143Hmb
Transgene Detail
Summary
Symbol: Tg(Kit-cre)143Hmb
Name: transgene insertion 143, Dan Holmberg
MGI ID: MGI:3036304
Synonyms: c-kit (143) Cre Tg
Transgene: Tg(Kit-cre)143Hmb  Location: unknown  
Alliance: Tg(Kit-cre)143Hmb page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Kit-cre)143Hmb expression driven by 1 gene
 
Mutation details: This transgene expresses Cre recombinase under the control of a mouse Kit promoter. In this line, expression of cre was noted in late spermatogenesis, oogenesis and early embryogenesis. Functional analysis of recombinase activity determined that deletion of a floxed reporter gene occurred in a mosaic pattern in all tissues tested. The degree of mosaicism was consistent within an individual, but varied dramatically between individuals. (J:88598)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Kit (mouse)
Summary of all recombinase alleles driven by Kit.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:88598 Bergqvist I, et al., Transgenic Cre recombinase expression in germ cells and early embryogenesis directs homogeneous and ubiquitous deletion of loxP-flanked gene segments. FEBS Lett. 1998 Oct 30;438(1-2):76-80
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory