Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Cryaa-cre)10Mlr
Name:	transgene insertion 10, Mike Robinson
MGI ID:	MGI:3038243
Synonyms:	CPV14/Cre, cry-cre, Mlr10, MLR10-Cre
Transgene:	Tg(Cryaa-cre)10Mlr  Location: unknown
Alliance:	Tg(Cryaa-cre)10Mlr page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Cryaa-cre)10Mlr expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Cryaa (MGI:88515)   Mutation details: The expression of sequence encoding cre recombinase was driven by a modified alpha A crystallin promoter. The promoter consists of -282/+43 of the mouse Cryaa gene with an inserted copy of Pax6 consensus binding site in a 5' to 3' orientation at position -86 of the promoter. Seven lines were created with this line having expression of the transgene in both the lens epithelium and lens fiber cells but not in other parts of the eye. (J:88422, J:90292)

Activity:	Tissue activity of this recombinase allele
Driver:	Cryaa (mouse) Summary of all recombinase alleles driven by Cryaa. Comparative matrix view of recombinase activities Alliance mouse Cryaa gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

390 assay results 6 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:88422 Ebong S, et al., Characterization of the roles of STAT1 and STAT3 signal transduction pathways in mammalian lens development. Mol Vis. 2004 Feb 19;10:122-31
All:	56 reference(s)