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Tg(Bglap2-cre)2Kry
Transgene Detail
Summary
Symbol: Tg(Bglap2-cre)2Kry
Name: transgene insertion 2, Gerard Karsenty
MGI ID: MGI:3041872
Synonyms: artificial OG2-Cre
Transgene: Tg(Bglap2-cre)2Kry  Location: unknown  
Alliance: Tg(Bglap2-cre)2Kry page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Bglap2-cre)2Kry expression driven by 1 gene
 
Mutation detailsAn engineered promoter region was derived from the Bglap2 proximal region, consisting of 6 copies of two osteoblast-specific cis-acting elements, OSE2 and OSE1. This promoter region was adjoined to sequence encoding cre recombinase, which was expressed in both bone and cartilage tissue. (J:77071)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Bglap2 (species not specified)
Summary of all recombinase alleles driven by Bglap2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:77071 Dacquin R, et al., Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast. Dev Dyn. 2002 Jun;224(2):245-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory