About   Help   FAQ
Bmp4tm1.1Jfm
Targeted Allele Detail
Summary
Symbol: Bmp4tm1.1Jfm
Name: bone morphogenetic protein 4; targeted mutation 1.1, James F Martin
MGI ID: MGI:3042751
Synonyms: Bmp4null
Gene: Bmp4  Location: Chr14:46620982-46628126 bp, - strand  Genetic Position: Chr14, 23.95 cM
Alliance: Bmp4tm1.1Jfm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89237
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: Cre-mediated excision of the loxP flanked exon 4 sequences of Bmp4tm1Jfm left a single loxP site in place of exon 4. (J:89237)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 32 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp4 Mutation:  23 strains or lines available
References
Original:  J:89237 Liu W, et al., Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4489-94
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory