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Hey1tm1Gess
Targeted Allele Detail
Summary
Symbol: Hey1tm1Gess
Name: hairy/enhancer-of-split related with YRPW motif 1; targeted mutation 1, Manfred Gessler
MGI ID: MGI:3043217
Synonyms: Hey1-
Gene: Hey1  Location: Chr3:8728419-8732098 bp, - strand  Genetic Position: Chr3, 2.15 cM
Alliance: Hey1tm1Gess page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:89444
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: An in-frame lacZ gene replaced all of exons 2-4 and parts of exons 1 and 5 via homologous recombination. Expression of beta-galactosidase activity is similar to endogenous Hey1 expression. (J:89444)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hey1 Mutation:  17 strains or lines available
References
Original:  J:89444 Fischer A, et al., The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004 Apr 15;18(8):901-11
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory