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Tg(Vav1-cre)1Awr
Transgene Detail
Summary
Symbol: Tg(Vav1-cre)1Awr
Name: transgene insertion 1, Andrew W Roberts
MGI ID: MGI:3043860
Synonyms: vavCre, VavCreCroker
Transgene: Tg(Vav1-cre)1Awr  Location: unknown  
Alliance: Tg(Vav1-cre)1Awr page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Vav1-cre)1Awr expression driven by 1 gene
 
Mutation details: Sequence encoding nls-cre was adjoined to Vav1 promoter sequence. Cre activity was detected in hematopoietic cells including greater than 99% of neutrophils, macrophages, T cells and greater than 90% of B cells and nucleated erythroid cells. Activity was also detected in endothelial cells, and testes. (J:89785)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Vav1 (species not specified)
Summary of all recombinase alleles driven by Vav1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:89785 Croker BA, et al., SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. Immunity. 2004 Mar;20(2):153-65
All:  17 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory