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Sqstm1tm1Jmos
Targeted Allele Detail
Summary
Symbol: Sqstm1tm1Jmos
Name: sequestosome 1; targeted mutation 1, Jorge Moscat
MGI ID: MGI:3043976
Synonyms: p62-
Gene: Sqstm1  Location: Chr11:50090193-50101654 bp, - strand  Genetic Position: Chr11, 30.36 cM, cytoband B1.2
Alliance: Sqstm1tm1Jmos page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90010
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 1 was replaced with a neomycin selection cassette. Protein was undetected by Western blot analysis of homozygous mutant embryonic fibroblasts. (J:90010)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sqstm1 Mutation:  35 strains or lines available
References
Original:  J:90010 Duran A, et al., The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. Dev Cell. 2004 Feb;6(2):303-9
All:  21 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory