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Ren1tm2(cre)Gom
Targeted Allele Detail
Summary
Symbol: Ren1tm2(cre)Gom
Name: renin 1 structural; targeted mutation 2, R Ariel Gomez
MGI ID: MGI:3044909
Synonyms: Ren1d, Ren1d-Cre, Ren1dCre
Gene: Ren1  Location: Chr1:133278412-133288058 bp, + strand  Genetic Position: Chr1, 57.91 cM
Alliance: Ren1tm2(cre)Gom page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90571
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ren1tm2(cre)Gom expression driven by 1 gene
 
Mutation details: Exons 1 through 7 were replaced by homologous recombination with a cassette containing cre and neo. Cre recombinase activity was confirmed in crosses with mice carrying floxed lacZ or GFP reporters. (J:90571)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ren1 (mouse)
Summary of all recombinase alleles driven by Ren1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ren1 Mutation:  35 strains or lines available
References
Original:  J:90571 Sequeira Lopez ML, et al., Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Dev Cell. 2004 May;6(5):719-28
All:  33 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory