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Or4e5tm1(cre)Rax
Targeted Allele Detail
Summary
Symbol: Or4e5tm1(cre)Rax
Name: olfactory receptor family 4 subfamily E member 5; targeted mutation 1, Richard Axel
MGI ID: MGI:3046829
Synonyms: MOR28-IRES-Cre
Gene: Or4e5  Location: Chr14:52727392-52733152 bp, - strand  Genetic Position: Chr14, 26.97 cM
Alliance: Or4e5tm1(cre)Rax page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90717
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Or4e5tm1(cre)Rax expression driven by 1 gene
 
Mutation details: A cassette containing an IRES-Cre and FRT-flanked neo was inserted 50 bp upstream of the stop codon. Southern blot confirmed recombination. Immunohistochemistry indicated that cells expressing the endogenous gene also expressed Cre. (J:90717)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Or4e5 (mouse)
Summary of all recombinase alleles driven by Or4e5.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Or4e5 Mutation:  20 strains or lines available
References
Original:  J:90717 Shykind BM, et al., Gene switching and the stability of odorant receptor gene choice. Cell. 2004 Jun 11;117(6):801-15
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory