Tg(MMTV-vHaras)4aPjo
Transgene Detail
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| Symbol: |
Tg(MMTV-vHaras)4aPjo |
| Name: |
transgene insertion 4a, Paul Jolicoeur |
| MGI ID: |
MGI:3047122 |
| Synonyms: |
MMTV/v-Ha-ras, MR4A |
| Transgene: |
Tg(MMTV-vHaras)4aPjo Location: unknown
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| Alliance: |
Tg(MMTV-vHaras)4aPjo page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: This transgene contains the mouse mammary tumor virus promoter and an allele of the v-Ha-ras (Harvey rat sarcoma) viral oncogene carrying two activating point mutations: one in codon 12, Gly12Arg, and one in codon 59, Ala59Thr.
(J:46456, J:90327)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Founders 2, 3, 4b, and 5 were also produced. Line 4a females on a genetic background that involves (C3H x C57BL/6)F2 and BALB/cJ did not develop mammary gland adenocarcinomas. |
| Original: |
J:46456 Tremblay PJ, et al., Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues. Mol Cell Biol. 1989 Feb;9(2):854-9 |
| All: |
2 reference(s) |
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Analysis Tools
