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Gene Expression Data
Assay Details
Assay
Reference: J:91609 Araki T, et al., Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation. Nat Med. 2004 Aug;10(8):849-57
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3051680
Gene symbol: Mapk3
Gene name: mitogen-activated protein kinase 3
Antibody: anti-Phospho-p44/42 MAP Kinase (Thr202/Tyr204) antibody (#9101)
Assay notes: The antibody used in this study recognizes both phosphorylated Mapk1 and phosphorylated Mapk3.
Results
Specimen WT a: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb Present 6a WT
TS19: head Present 6a WT Expression is in the face.
Specimen Ptpn11D61G/+: embryonic day 11.5; Ptpn11tm1Bgn/Ptpn11+ (more )
Structure Level Pattern Image Note
TS19: limb Strong 6a Ptpn11D61G/+
TS19: head Strong 6a Ptpn11D61G/+ Expression is in the face.
Specimen WT b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: endocardial cushion Present Single cells 6b WT
Specimen Ptpn11D61G/+ middle: embryonic day 11.5; Ptpn11tm1Bgn/Ptpn11+ (more )
Structure Level Pattern Image Note
TS19: endocardial cushion Strong Single cells 6b middle panel More cells stain than in wild-type embryos.
Specimen Ptpn11D61G/+ right: embryonic day 11.5; Ptpn11tm1Bgn/Ptpn11+ (more )
Structure Level Pattern Image Note
TS19: endocardial cushion Strong Single cells 6b right panel More cells stain than in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
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