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Ciapin1tm1Yzka
Targeted Allele Detail
Summary
Symbol: Ciapin1tm1Yzka
Name: cytokine induced apoptosis inhibitor 1; targeted mutation 1, Yuzuru Kanakura
MGI ID: MGI:3051894
Gene: Ciapin1  Location: Chr8:95546432-95564986 bp, - strand  Genetic Position: Chr8, 46.86 cM
Alliance: Ciapin1tm1Yzka page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:90889
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 1 was replaced by a neomycin resistance gene in the targeting construct. Southern blot and PCR confirmed recombination in mutant mice and Western blot indicated gene expression was reduced in heterozygotes and completely lost in homozygous mutants. (J:90889)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ciapin1 Mutation:  29 strains or lines available
References
Original:  J:90889 Shibayama H, et al., Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis. J Exp Med. 2004 Feb 16;199(4):581-92
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory