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Hexim1tm1Maqs
Targeted Allele Detail
Summary
Symbol: Hexim1tm1Maqs
Name: hexamethylene bis-acetamide inducible 1; targeted mutation 1, M A Q Siddiqui
MGI ID: MGI:3052225
Synonyms: CLP-1-, Cpl1tm1Maqs
Gene: Hexim1  Location: Chr11:103007151-103010551 bp, + strand  Genetic Position: Chr11, 66.71 cM
Alliance: Hexim1tm1Maqs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92209
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A neomycin resistance gene replaced the coding exon. Northern blot of livers indicated lack of transcript in mutant mice. (J:92209)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 47 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hexim1 Mutation:  10 strains or lines available
References
Original:  J:92209 Huang F, et al., Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory