Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tg(Neurog3-cre)C1Able
Name:	transgene insertion C1, Andrew B Leiter
MGI ID:	MGI:3052639
Synonyms:	Neurgo3TgBAC-Cre, Neurog3(cre), Neurog3Cre, ngn3-Cre, Tg(Neurog3-cre)#Able
Transgene:	Tg(Neurog3-cre)C1Able  Location: unknown
Alliance:	Tg(Neurog3-cre)C1Able page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Neurog3-cre)C1Able expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Neurog3 (MGI:893591)   Mutation details: The Cre recombinase coding sequence, flanked by a nuclear localization signal and an SV40 polyadenylation site, was inserted just after the translation start site of the neurogenin 3 gene present in mouse BAC RP23-121F10, which also includes approximately 81 kb of 5' and 102 kb of 3' flanking DNA. Immunohistochemical analysis shows the same expression pattern for cre as for neurogenin 3 in adult and embryonic mice bearing this transgene. Cre recombinase activity is seen in cell types of pancreas, stomach, small intestine and colon that express or are descended from cells that express neurogenin 3 during development. (J:92204)

Activity:	Tissue activity of this recombinase allele
Driver:	Neurog3 (mouse) Summary of all recombinase alleles driven by Neurog3. Comparative matrix view of recombinase activities Alliance mouse Neurog3 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

16 assay results 7 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:92204 Schonhoff SE, et al., Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types. Dev Biol. 2004 Jun 15;270(2):443-54
All:	92 reference(s)