Cat<b> Radiation induced Allele Detail MGI Mouse (MGI:3053604)

Cat^b
Radiation induced Allele Detail

Summary

Symbol:	Cat^b
Name:	catalase; acatalasemia
MGI ID:	MGI:3053604
Synonyms:	Cs^b, M1
Gene:	Cat Location: Chr2:103284249-103315498 bp, - strand Genetic Position: Chr2, 54.43 cM
Alliance:	Cat^b page

Mutation
origin

Strain of Origin:

(101 x C3H)F1

Mutation
description

Allele Type:		Radiation induced
Mutation:		Nucleotide substitutions
		Mutation details: This allele corresponds to a mutation located in the first alpha helix in the amino terminal arm of the catalase subunit. The substitution of G to T results in an amino acid substitution that replaces glutamine with histidine at position 11. (J:10926)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Cat Mutation:	30 strains or lines available

References

Original:	J:5015 Feinstein RN, et al., Acatalasemic and hypocatalasemic mouse mutants. Genetics. 1966 May;53(5):923-33
All:	21 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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