About   Help   FAQ
Tg(AQP2-cre)2Dek
Transgene Detail
Summary
Symbol: Tg(AQP2-cre)2Dek
Name: transgene insertion 2, Donald E Kohan
MGI ID: MGI:3054057
Transgene: Tg(AQP2-cre)2Dek  Location: unknown  
Alliance: Tg(AQP2-cre)2Dek page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(AQP2-cre)2Dek expression driven by 1 gene
 
Mutation details: This transgene consists of 14 kb from the 5'-flanking region of the human AQP2 driving expression of a modified cre recombinase that includes an SV40 nuclear localization signal and an 11 amino acid herpes simplex virus glycoprotein D epitope tag. Cre expression is seen in the collecting ducts of the kidney, the vas deferens, and the testis including post-meiotic sperm. Paternal inheritance of this transgene results in ubiquitous cre mediated recombination. (J:52357)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: AQP2 (human)
Summary of all recombinase alleles driven by AQP2.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:52357 Nelson RD, et al., Expression of an AQP2 Cre recombinase transgene in kidney and male reproductive system of transgenic mice. Am J Physiol. 1998 Jul;275(1 Pt 1):C216-26
All:  28 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory