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Npas3tm1Slm
Targeted Allele Detail
Summary
Symbol: Npas3tm1Slm
Name: neuronal PAS domain protein 3; targeted mutation 1, Steven l McKnight
MGI ID: MGI:3054783
Synonyms: Npas3-
Gene: Npas3  Location: Chr12:53294940-54118958 bp, + strand  Genetic Position: Chr12, 22.31 cM, cytoband C1
Alliance: Npas3tm1Slm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:92610
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
    Immunohistochemistry confirms the absence of protein expression in the CNS in homozygotes. (J:92610)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Npas3 Mutation:  41 strains or lines available
References
Original:  J:92610 Erbel-Sieler C, et al., Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13648-53
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory