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Tg(Pcp2-SCA2)11Plt
Transgene Detail
Summary
Symbol: Tg(Pcp2-SCA2)11Plt
Name: transgene insertion 11, Stefan M Pulst
MGI ID: MGI:3505741
Synonyms: Q58-11, Tg(Pcp2SCA2)11Plt
Transgene: Tg(Pcp2-SCA2)11Plt  Location: unknown  
Alliance: Tg(Pcp2-SCA2)11Plt page
Transgene
origin
Strain of Origin:  (C57BL/6J x DBA/2J)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Pcp2-SCA2)11Plt expresses 1 gene
 
Mutation detailsThe transgene contains a full length human spinocerebellar ataxia 2 (SCA2) cDNA (with a 58 CAG repeat) as well as the mouse Pcp2 (Purkinje cell protein 2) promoter, untranslated, and poly(A) sequences. Transcripts and protein product are detected in the cerebellum. (J:93869)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:93869 Huynh DP, et al., Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human. Nat Genet. 2000 Sep;26(1):44-50
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory