About   Help   FAQ
Gcgrtm1Mjch
Targeted Allele Detail
Summary
Symbol: Gcgrtm1Mjch
Name: glucagon receptor; targeted mutation 1, M J Charron
MGI ID: MGI:3505881
Synonyms: Gcgr-
Gene: Gcgr  Location: Chr11:120421525-120429812 bp, + strand  Genetic Position: Chr11, 84.24 cM, cytoband E2
Alliance: Gcgrtm1Mjch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81772
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 3-6 were replaced with a PGK-neo. (J:81772)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcgr Mutation:  8 strains or lines available
References
Original:  J:81772 Gelling RW, et al., Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1438-43
All:  46 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory