Chd7<Flo> Chemically induced Allele Detail MGI Mouse (MGI:3511552)

Chd7^Flo
Chemically induced Allele Detail

Summary

Symbol:	Chd7^Flo
Name:	chromodomain helicase DNA binding protein 7; flouncer
MGI ID:	MGI:3511552
Synonyms:	WBE2
Gene:	Chd7 Location: Chr4:8690406-8867659 bp, + strand Genetic Position: Chr4, 3.68 cM
Alliance:	Chd7^Flo page

Mutation
origin

Strain of Origin:

C3HeB/FeJ

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Nucleotide substitutions
		Mutation details: A mutation in the splice donor site resulted in the S1864X substitution. This mutation putatively results in a protein lacking only the most C-terminal NLS, SANT, and BRK domains. (J:104123)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Chd7 Mutation:	138 strains or lines available

References

Original:	J:93173 Pau H, et al., Characterization of a new mouse mutant, flouncer, with a balance defect and inner ear malformation. Otol Neurotol. 2004 Sep;25(5):707-13
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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