Klf11<tm1Czs> Targeted Allele Detail MGI Mouse (MGI:3513147)

About Help FAQ

Klf11^tm1Czs
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Klf11^tm1Czs
Name:	Kruppel-like transcription factor 11; targeted mutation 1, Chao-Zhong Song
MGI ID:	MGI:3513147
Synonyms:	KLF11-
Gene:	Klf11 Location: Chr12:24701370-24712781 bp, + strand Genetic Position: Chr12, 8.49 cM
Alliance:	Klf11^tm1Czs page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:94499
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: Most of exons 3 and 4 were replaced by a PGK-neomycin resistance cassette. RT-PCR confirmed that transcription no longer occurred. (J:94499)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Klf11 Mutation:	35 strains or lines available

References

Original:	J:94499 Song CZ, et al., Functional study of transcription factor KLF11 by targeted gene inactivation. Blood Cells Mol Dis. 2005 Jan-Feb;34(1):53-9
All:	19 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24