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Lhx3tm1(cre)Slp
Targeted Allele Detail
Summary
Symbol: Lhx3tm1(cre)Slp
Name: LIM homeobox protein 3; targeted mutation 1, Samuel L Pfaff
MGI ID: MGI:3513299
Synonyms: Lhx3Cre, Lhx3:CRE
Gene: Lhx3  Location: Chr2:26090224-26098261 bp, - strand  Genetic Position: Chr2, 18.44 cM, cytoband A2-C1
Alliance: Lhx3tm1(cre)Slp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:51420
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Lhx3tm1(cre)Slp expression driven by 1 gene
 
Mutation details: An IRES_CRE_NEO cassette was cloned into the 3' untranslated region. Gene expression was not disrupted. (J:51420)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lhx3 (mouse)
Summary of all recombinase alleles driven by Lhx3.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 14 assay results
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx3 Mutation:  26 strains or lines available
References
Original:  J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
All:  13 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory