Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	MtapGt(RRK081)Byg
Name:	methylthioadenosine phosphorylase; gene trap RRK081, BayGenomics
MGI ID:	MGI:3514132
Synonyms:	MtaplacZ
Gene:	Mtap  Location: Chr4:89055607-89099327 bp, + strand  Genetic Position: Chr4, 42.15 cM, cytoband C4
Alliance:	MtapGt(RRK081)Byg page

Mutant Cell Line:	RRK081
Germline Transmission:	Earliest citation of germline transmission: J:123675
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: pGT2Lxf     Vector Type: gene trap     The pGT2Lxf gene trap vector inserted into intron 2. (J:123675) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select RRK081 CC894178 (MGI Seq Detail) 5' RACE Chr4:89055643-89066509 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 5 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

List all tumor models in MMHCdb carrying MtapGt(RRK081)Byg

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mtap Mutation:	18 strains or lines available

Original:	J:123675 Williamson RE, et al., Methylthioadenosine phosphorylase (MTAP) in hearing: gene disruption by chromosomal rearrangement in a hearing impaired individual and model organism analysis. Am J Med Genet A. 2007 Jul 15;143(14):1630-9
All:	6 reference(s)