Nr2f1<tm1Mist> Targeted Allele Detail MGI Mouse (MGI:3521756)

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Nr2f1^tm1Mist
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Nr2f1^tm1Mist
Name:	nuclear receptor subfamily 2, group F, member 1; targeted mutation 1, Michele Studer
MGI ID:	MGI:3521756
Synonyms:	COUP-TF1^null
Gene:	Nr2f1 Location: Chr13:78337090-78346954 bp, - strand Genetic Position: Chr13, 41.38 cM
Alliance:	Nr2f1^tm1Mist page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:114098
Parent Cell Line:	TBV2 (ES Cell)
Strain of Origin:	129S2/SvPas

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Intragenic deletion
		Exon 3 was flanked by loxP sites and removed via transient cre expression. (J:114098)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Nr2f1 Mutation:	25 strains or lines available

References

Original:	J:114098 Armentano M, et al., COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth. Development. 2006 Nov;133(21):4151-62
All:	6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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