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Ephb6tm1Jwu
Targeted Allele Detail
Summary
Symbol: Ephb6tm1Jwu
Name: Eph receptor B6; targeted mutation 1, Jiangping Wu
MGI ID: MGI:3522020
Synonyms: Eph6b-
Gene: Ephb6  Location: Chr6:41582416-41597443 bp, + strand  Genetic Position: Chr6, 19.77 cM
Alliance: Ephb6tm1Jwu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94701
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A sequence from the ATG in exon 3 thru the 5' end of intron 4 ws replaced with a GFP-neo cassette. Mutants demonstrated no transcript expression but did express GFP driven by the endogenous promoter. (J:94701)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ephb6 Mutation:  54 strains or lines available
References
Original:  J:94701 Luo H, et al., EphB6-null mutation results in compromised T cell function. J Clin Invest. 2004 Dec;114(12):1762-73
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory