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Tg(Gfap-cre)73.12Mvs
Transgene Detail
Summary
Symbol: Tg(Gfap-cre)73.12Mvs
Name: transgene insertion 73.12, Michael V Sofroniew
MGI ID: MGI:3522215
Synonyms: GFAP-Cre, mGFAP-Cre, mGFAPCre
Transgene: Tg(Gfap-cre)73.12Mvs  Location: unknown  
Alliance: Tg(Gfap-cre)73.12Mvs page
Transgene
origin
Strain of Origin:  (BALB/c x C57BL/6NHsd)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gfap-cre)73.12Mvs expression driven by 1 gene
 
Mutation details: The bacterial Cre recombinase gene was inserted into the first exon of an expression cassette (clone 445) that contains all the introns, promoter regulatory elements, exons, and 2.5 kb of 5' and 2 kb of 3' flanking DNA of the astroglia-specific mouse glial fibrillary acidic protein gene. GFAP is not expressed from the transgene due to deletion of part of exon 1. (J:94543)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gfap (mouse)
Summary of all recombinase alleles driven by Gfap.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:94543 Garcia AD, et al., GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci. 2004 Nov;7(11):1233-41
All:  110 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory