About   Help   FAQ
Myh9tm1Maco
Targeted Allele Detail
Summary
Symbol: Myh9tm1Maco
Name: myosin, heavy polypeptide 9, non-muscle; targeted mutation 1, Mary Anne Conti
MGI ID: MGI:3522434
Synonyms: A-
Gene: Myh9  Location: Chr15:77644788-77726315 bp, - strand  Genetic Position: Chr15, 36.81 cM
Alliance: Myh9tm1Maco page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94940
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details: A PGK-neomycin cassette was inserted in exon 3. Absence of gene products was confirmed by Northern and Western blot analysis and by immunohistochemistry. (J:94940)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myh9 Mutation:  219 strains or lines available
References
Original:  J:94940 Conti MA, et al., Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem. 2004 Oct 1;279(40):41263-6
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory