Pde4a<tm1Mct> Targeted Allele Detail MGI Mouse (MGI:3525068)

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Pde4a^tm1Mct
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Pde4a^tm1Mct
Name:	phosphodiesterase 4A, cAMP specific; targeted mutation 1, Marco Conti
MGI ID:	MGI:3525068
Synonyms:	PDE4A^-
Gene:	Pde4a Location: Chr9:21077010-21124544 bp, + strand Genetic Position: Chr9, 7.73 cM
Alliance:	Pde4a^tm1Mct page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:94853
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutation:		Not Specified
		No molecular information has been published.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Pde4a Mutation:	39 strains or lines available

References

Original:	J:94853 Ariga M, et al., Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation. J Immunol. 2004 Dec 15;173(12):7531-8
All:	12 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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