Ptf1atm1Mgn
Targeted Allele Detail
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| Symbol: |
Ptf1atm1Mgn |
| Name: |
pancreas specific transcription factor, 1a; targeted mutation 1, Mark A Magnuson |
| MGI ID: |
MGI:3526067 |
| Synonyms: |
Ptf1aLCA |
| Gene: |
Ptf1a Location: Chr2:19450474-19452312 bp, + strand Genetic Position: Chr2, 13.37 cM, cytoband A2
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| Alliance: |
Ptf1atm1Mgn page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:306470
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| Parent Cell Line: |
TL1/TL-1 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Null/knockout, RMCE-ready) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 and 2 were replaced with a floxed neo cassette. This insertion results in the floxed cassette acceptor (LCA) available for recombinase-mediated cassette exchange (RMCE).
(J:135698)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ptf1a Mutation: |
31 strains or lines available
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| Original: |
J:135698 Burlison JS, et al., Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol. 2008 Apr 1;316(1):74-86 |
| All: |
2 reference(s) |
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Analysis Tools
