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Drd1tm1(cre)Rpa
Targeted Allele Detail
Summary
Symbol: Drd1tm1(cre)Rpa
Name: dopamine receptor D1; targeted mutation 1, Richard D Palmiter
MGI ID: MGI:3527153
Synonyms: Dr1-Cre, Drd1a-Cre
Gene: Drd1  Location: Chr13:54205202-54209677 bp, - strand  Genetic Position: Chr13, 28.4 cM
Alliance: Drd1tm1(cre)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138586
Parent Cell Line:  AK18.1 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Drd1tm1(cre)Rpa expression driven by 1 gene
 
Mutation details: A cassette containing a cre gene with a nuclear localization signal and an IRES-EGFP was inserted into the open reading frame. (J:138586)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Drd1 (mouse)
Summary of all recombinase alleles driven by Drd1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Drd1 Mutation:  70 strains or lines available
References
Original:  J:138586 Heusner CL, et al., Deletion of GAD67 in dopamine receptor-1 expressing cells causes specific motor deficits. Genesis. 2008 Jul;46(7):357-67
All:  16 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory