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Mapk8ip3tm1Plhn
Targeted Allele Detail
Summary
Symbol: Mapk8ip3tm1Plhn
Name: mitogen-activated protein kinase 8 interacting protein 3; targeted mutation 1, Pyung-Lim Han
MGI ID: MGI:3527900
Synonyms: jsap1-
Gene: Mapk8ip3  Location: Chr17:25116480-25155951 bp, - strand  Genetic Position: Chr17, 12.53 cM
Alliance: Mapk8ip3tm1Plhn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95744
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A PGK-neo in reverse orientation replaced coding sequence, including the leucine-zipper domain. Northern blot confirmed absence of transcript for this part of the gene in mutant brain samples. (J:95744)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 48 assay results
In Structures Affected by this Mutation: 22 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk8ip3 Mutation:  53 strains or lines available
References
Original:  J:95744 Ha HY, et al., The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1. Dev Biol. 2005 Jan 1;277(1):184-99
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory