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En1tm7(cre/ESR1)Alj
Targeted Allele Detail
Summary
Symbol: En1tm7(cre/ESR1)Alj
Name: engrailed 1; targeted mutation 7, Alexandra L Joyner
MGI ID: MGI:3528251
Synonyms: En1-CreERT1, En1-CreERT1, En1tm7(cre)Alj, Engrailed1-Cre
Gene: En1  Location: Chr1:120530246-120535719 bp, + strand  Genetic Position: Chr1, 52.74 cM, cytoband C2-qter
Alliance: En1tm7(cre/ESR1)Alj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:95823
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
En1tm7(cre/ESR1)Alj expression driven by 1 gene
 
Mutation details: A tamoxifen dependent form of cre recombinase (CreER) and a loxP-flanked neo in reverse orientation were inserted into the locus. The neo was removed in vivo via Cre-mediated recombination. (J:95823)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: En1 (mouse)
Summary of all recombinase alleles driven by En1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any En1 Mutation:  34 strains or lines available
References
Original:  J:95823 Sgaier SK, et al., Morphogenetic and cellular movements that shape the mouse cerebellum; insights from genetic fate mapping. Neuron. 2005 Jan 6;45(1):27-40
All:  14 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory