Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Pax3tm1(cre)Joe
Name:	paired box 3; targeted mutation 1, Jonathan A Epstein
MGI ID:	MGI:3573783
Synonyms:	Pax3-Cre, Pax3Cre, Pax3Cre-KI
Gene:	Pax3  Location: Chr1:78077904-78173771 bp, - strand  Genetic Position: Chr1, 39.79 cM
Alliance:	Pax3tm1(cre)Joe page

Germline Transmission:	Earliest citation of germline transmission: J:96431
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Pax3tm1(cre)Joe expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pax3 (MGI:97487)   Mutation details: A targeting vector was desinged to insert the cre recombinase cDNA followed by a stop codon and a polyA signal in place of exon 1 of the endogenous locus. (J:96431, J:98272)

Activity:	Tissue activity of this recombinase allele
Driver:	Pax3 (mouse) Summary of all recombinase alleles driven by Pax3. Comparative matrix view of recombinase activities Alliance mouse Pax3 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	120 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax3 Mutation:	50 strains or lines available

Original:	J:96431 Lang D, et al., Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature. 2005 Feb 24;433(7028):884-7
All:	131 reference(s)